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Reprod Biomed Online. 2017 Sep;35(3):287-295. doi: 10.1016/j.rbmo.2017.05.021. Epub 2017 Jun 21.

Assisted reproduction techniques in Latin America: the Latin American Registry, 2014.

Author information

1
Unit of Reproductive Medicine Clínica Las Condes, Lo Fontecilla 441, Santiago, Chile; Program of Ethics and Public Policies in Human Reproduction, University Diego Portales, Ejercito 260, Santiago, Chile; Latin American Network of Assisted Reproduction (REDLARA), Plaza Independencia 811, Montevideo, Uruguay. Electronic address: fzegers@clc.cl.
2
Latin American Network of Assisted Reproduction (REDLARA), Plaza Independencia 811, Montevideo, Uruguay; Unit of Reproductive Medicine Clínica Monteblanco, Camino Farellones 18780 Santiago, Chile.
3
Unit of Reproductive Medicine Clínica Las Condes, Lo Fontecilla 441, Santiago, Chile; Latin American Network of Assisted Reproduction (REDLARA), Plaza Independencia 811, Montevideo, Uruguay.
4
Latin American Network of Assisted Reproduction (REDLARA), Plaza Independencia 811, Montevideo, Uruguay; Unifertes, Av. San Juan Bosco, Caracas, Venezuela.

Abstract

Multinational data on assisted reproduction techniques (IVF and intractytoplasmic sperm injection [ICSI], frozen embryo transfer, oocyte donation, preimplantation genetic diagnosis and fertility preservation) were collected from 159 institutions in 15 Latin American countries. A total of 41.34% of IVF-ICSI cycles were conducted in women aged 35-39 years and 23.35% in women aged 40 years and older. After removing freeze-all cases, delivery rate per oocyte retrieval was 25.05% for ICSI and 27.41% for IVF. Multiple births included 20.78% twins and 0.92% triplets and over. In oocyte donation, twins reached 28.93% and triplets 1.07%. Preterm deliveries reached 16.4% in singletons, 55.02% in twins and 76% in triplets. Perinatal mortality in 18,162 births was 23 per 1000 in singletons, 35 per 1000 in twins, and 36 per 1000 in high-order multiples. Elective single embryo transfer represented 2.63% of fresh transfers, with a 32.15% delivery rate per transfer. Elective double embryo transfer represented 23.74% of transfers, with a 41.03% delivery rate per transfer; 11,373 babies (62.6%) were singletons; 6398 (35.2%) twins, and 391 (2.2%), triplets and more. Given the effect of multiple births on prematurity, morbidity and perinatal mortality, reinforcing the existing trend of reducing the number of embryos transferred is mandatory.

KEYWORDS:

Assisted reproductive technology; Epidemiology; IVF–ICSI; Latin America; Perinatal outcome; Registry

PMID:
28687208
DOI:
10.1016/j.rbmo.2017.05.021
[Indexed for MEDLINE]

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