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Fam Cancer. 2018 Apr;17(2):209-212. doi: 10.1007/s10689-017-0018-6.

A new hereditary colorectal cancer network in the Middle East and eastern mediterranean countries to improve care for high-risk families.

Author information

1
Department of Gastroenterology and Hepatology, Leiden University Medical Centre & Netherlands Foundation for the Detection of Hereditary Tumours, Leiden, The Netherlands.
2
Patient's Friends Society, Jerusalem, Palestine.
3
Hebron University, Hebron, Palestine.
4
Department of Gastroenterology, Makased Islamic Charitable Hospital, Jerusalem, Palestine.
5
Department of Internal Medicine, Arabcare Hospital, Ramallah, Palestine.
6
Department of Gastroenterology, St. George Hospital Medical Center, University of Balamand Medical School, Beirut, Lebanon.
7
Division of Gastroenterology, American University of Beirut Medical Center, Beirut, Lebanon.
8
Department of Pediatrics, Makased Islamic Charitable Hospital, Jerusalem, Palestine.
9
Department of Surgery, Agusta Victoria Hospital, Jerusalem, Palestine.
10
Colorectal Research Center, Iran University of Medical Sciences, Tehran, Iran.
11
Motamed Cancer Institute, ACECR, Tehran, Iran.
12
Department of Internal Medicine and Gastroenterology, University of Acibadem, Acibadem Kozyatagi Hospital, Istanbul, Turkey.
13
Laboratory of Biology and Molecular Genetics, Faculty of Medicine, University 3, Constantine, Algeria.
14
Department of Gastroenterology, The Royal Hospital, Amman, Jordan.
15
Department of Internal Medicine, Creighton University, Omaha, USA.
16
Genetic Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.
17
Creighton's Hereditary Cancer Center, Creighton University, Omaha, USA.
18
Department of Gastroenterology & Hepatology, Leiden University Medical Centre, P.O. Box 9600, 2300 RC, Leiden, The Netherlands. hfavasen@gmail.com.
19
Netherlands Foundation for the Detection of Hereditary Tumours, Leiden, The Netherlands. hfavasen@gmail.com.

Abstract

Colorectal cancer (CRC) has a very high incidence in the western world. Data from registries in the Middle East showed that the incidence of CRC is relatively low in these countries. However, these data also showed that CRC incidence has increased substantially over the past three decades and that a high proportion of cases are diagnosed at an early age (<50 years). In view of these findings, more attention should be paid to prevention. Because of the often limited financial resources, focused screening of individuals with hereditary CRC, in particular those with Lynch syndrome, appears to be the most cost-effective strategy. During recent meetings of the Palestinian Society of Gastroenterology and the Mediterranean Task force for Cancer Control (MTCC) in Jericho, and the Patient's Friends Society of Jerusalem in Hebron the issue of hereditary CRC in the Middle East was discussed and the idea was conceived to establish a network on hereditary colorectal cancer (HCCN-ME) with the goal of improving care for high-risk groups in the Middle East and (Eastern) Mediterranean Countries.

KEYWORDS:

CMMRD; Familial colorectal cancer; Health care; Identification; Lynch syndrome; Registry

PMID:
28685475
PMCID:
PMC5893664
DOI:
10.1007/s10689-017-0018-6
[Indexed for MEDLINE]
Free PMC Article

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