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J Voice. 2018 May;32(3):359-362. doi: 10.1016/j.jvoice.2017.05.017. Epub 2017 Jul 3.

Sarcoidosis Presenting as Bilateral Vocal Fold Immobility.

Author information

1
Head and Neck Regeneration Program, Center for Regenerative Medicine, Mayo Clinic, Phoenix, Arizona.
2
Department of Otorhinolaryngology, Mayo Clinic Arizona, Phoenix, Arizona.
3
Head and Neck Regeneration Program, Center for Regenerative Medicine, Mayo Clinic, Phoenix, Arizona; Department of Otorhinolaryngology, Mayo Clinic Arizona, Phoenix, Arizona. Electronic address: lott.david@mayo.edu.

Abstract

Bilateral true vocal fold paralysis is rarely attributable to inflammatory diseases. Sarcoidosis is a rare but important etiology of bilateral true vocal fold paralysis by compressive lymphadenopathy, granulomatous infiltration, and neural involvement. We describe the first reported case of sarcoidosis presenting as bilateral vocal fold immobility caused by direct fixation by granulomatous infiltration severe enough to necessitate tracheostomy insertion. In addition, we discuss the presentation, the pathophysiology, and the treatment of this disease with a review of the literature of previously reported cases of sarcoidosis-related vocal fold immobility. Sarcoidosis should therefore be an important consideration for the otolaryngologist's differential diagnosis of true vocal fold immobility.

KEYWORDS:

Bilateral vocal fold immobility; Laryngeal sarcoidosis; Neurosarcoidosis; Respiratory sarcoidosis; Sarcoidosis

PMID:
28684250
DOI:
10.1016/j.jvoice.2017.05.017
[Indexed for MEDLINE]

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