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Environ Toxicol Pharmacol. 2017 Sep;54:48-52. doi: 10.1016/j.etap.2017.06.013. Epub 2017 Jun 20.

Biosynthesis of vitamin C stabilized tin oxide nanoparticles and their effect on body weight loss in neonatal rats.

Author information

1
Department of Paediatrics, Affiliated Hospital of Shandong Medical College, Linyi 276004, Shandong, China.
2
Department of Paediatrics, Tengzhou Central People's Hospital, No. 181 Xingtan Road, Zaozhuang 277500, Shandong, China. Electronic address: LTucciarontag@yahoo.com.

Abstract

The green synthesis of tin oxide nanoparticles (SnO2 NPs) using vitamin C (Vc) as a reducing agent via a biosynthetic approach is described. The effect of Vc-stabilized SnO2 NPs on the body weight of neonatal rats is also studied. The prepared SnO2NPs were characterized using spectroscopic and microscopic instrumental techniques including transmission electron microscopy (TEM), UV-visible spectrophotometry (UV-vis), X-ray diffraction and Fourier transform infrared spectroscopy, which confirmed the formation of NPs. TEM images confirmed the formation of spherical NPs with a mean particle size of around 30nm. The body weight studies showed that vitamin-C stabilized SnO2 NPs promote a higher body weight gain compared to raw SnO2 NPs. It was also shown that Vc can counteract the decreased body weight caused by SnO2 NPs in neonatal rats.

KEYWORDS:

Body weight; SnO(2) NPs; Vitamin C

PMID:
28683349
DOI:
10.1016/j.etap.2017.06.013
[Indexed for MEDLINE]

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