Send to

Choose Destination
Environ Toxicol Pharmacol. 2017 Sep;54:48-52. doi: 10.1016/j.etap.2017.06.013. Epub 2017 Jun 20.

Biosynthesis of vitamin C stabilized tin oxide nanoparticles and their effect on body weight loss in neonatal rats.

Author information

Department of Paediatrics, Affiliated Hospital of Shandong Medical College, Linyi 276004, Shandong, China.
Department of Paediatrics, Tengzhou Central People's Hospital, No. 181 Xingtan Road, Zaozhuang 277500, Shandong, China. Electronic address:


The green synthesis of tin oxide nanoparticles (SnO2 NPs) using vitamin C (Vc) as a reducing agent via a biosynthetic approach is described. The effect of Vc-stabilized SnO2 NPs on the body weight of neonatal rats is also studied. The prepared SnO2NPs were characterized using spectroscopic and microscopic instrumental techniques including transmission electron microscopy (TEM), UV-visible spectrophotometry (UV-vis), X-ray diffraction and Fourier transform infrared spectroscopy, which confirmed the formation of NPs. TEM images confirmed the formation of spherical NPs with a mean particle size of around 30nm. The body weight studies showed that vitamin-C stabilized SnO2 NPs promote a higher body weight gain compared to raw SnO2 NPs. It was also shown that Vc can counteract the decreased body weight caused by SnO2 NPs in neonatal rats.


Body weight; SnO(2) NPs; Vitamin C

[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center