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Crit Rev Food Sci Nutr. 2017 Jul 5:1-12. doi: 10.1080/10408398.2017.1349731. [Epub ahead of print]

The future of nutrition: Nutrigenomics and nutrigenetics in obesity and cardiovascular diseases.

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a Department of Biochemistry and Molecular Biology-A , University of Murcia , Murcia , Spain.
b Department of Surgery, Hospital de la Vega Lorenzo Guirao , University of Murcia , Murcia , Spain.
c Department of Cardiology, Hospital Clínico Universitario Virgen de la Arrixaca (IMIB-Arrixaca) , Universidad de Murcia , Murcia , Spain.


Over time, the relationship between diet and health has aroused great interest, since nutrition can prevent and treat several diseases. It has been demonstrated that general recommendations on macronutrients and micronutrients do not affect to every individual in the same way because diet is an important environmental factor that interacts with genes. Thus, there is a growing necessity of improving a personalized nutrition to treat obesity and associated medical conditions, taking into account the interactions between diet, genes and health. Therefore, the knowledge of the interactions between the genome and nutrients at the molecular level, has led to the advent of nutritional genomics, which involves the sciences of nutrigenomics and nutrigenetics. In this review, we will comprehensively analyze the role of the most important genes associated with two interrelated chronic medical conditions, such as obesity and cardiovascular diseases.


Gene; cardiovascular diseases; nutrigenetics; nutrigenomics; obesity; polimorphism

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