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Pediatr Blood Cancer. 2017 Dec;64(12). doi: 10.1002/pbc.26690. Epub 2017 Jul 4.

Imaging and management of fetuses and neonates with alloimmune thrombocytopenia.

Author information

1
Division of Pediatric Radiology, Department of Radiology, New York Presbyterian Hospital/Weill Cornell Medical College, New York, New York.
2
Division of Newborn Medicine, Department of Pediatrics, New York Presbyterian Hospital/Weill Cornell Medical College, New York, New York.
3
Division of Pediatric Hematology/Oncology, Department of Pediatrics and Medicine, New York Presbyterian Hospital/Weill Cornell Medical College, New York, New York.

Abstract

Fetal and neonatal alloimmune thrombocytopenia (FNAIT) is the most common cause of severe neonatal thrombocytopenia and intracranial bleeding in term newborns. Intracranial hemorrhage (ICH) commonly results in death or severe, lasting neurologic disability. The timing of ICH is also important for management of the next affected pregnancy in cases of FNAIT. This manuscript reviews the advantages and disadvantages of the different radiologic methodologies to identify and characterize ICH. It discusses the limits of ultrasound and the advantages of magnetic resonance imaging allowing avoidance of the radiation associated with computed tomography (CT) scans.

KEYWORDS:

FNAIT; ICH; imaging

PMID:
28675682
DOI:
10.1002/pbc.26690
[Indexed for MEDLINE]

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