Format

Send to

Choose Destination
Nature. 1985 Dec 19;318(6047):635-41.

Primary structure and expression of a functional human glucocorticoid receptor cDNA.

Abstract

Identification of complementary DNAs encoding the human glucocorticoid receptor predicts two protein forms, of 777 (alpha) and 742 (beta) amino acids, which differ at their carboxy termini. The proteins contain a cysteine/lysine/arginine-rich region which may define the DNA-binding domain. Pure radiolabelled glucocorticoid receptor, synthesized in vitro, is immunoreactive and possesses intrinsic steroid-binding activity characteristic of the native glucocorticoid receptor.

PMID:
2867473
PMCID:
PMC6165583
DOI:
10.1038/318635a0
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for PubMed Central
Loading ...
Support Center