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Cogn Affect Behav Neurosci. 2017 Oct;17(5):1018-1027. doi: 10.3758/s13415-017-0529-5.

Trait compassion is associated with the neural substrate of empathy.

Author information

1
Key Laboratory of Cognition and Personality (SWU), Ministry of Education, Chongqing, 400715, China.
2
Department of Psychology, Southwest University, Beibei, Chongqing, 400715, China.
3
Centre for Addiction and Mental Health, Campbell Family Mental Health Research Institute, 250 College Street, Toronto, ON, M5T 1R8, Canada.
4
Department of Psychology, University of Minnesota, 75 East River Rd., Minneapolis, MN, 55455, USA. cdeyoung@umn.edu.
5
Key Laboratory of Cognition and Personality (SWU), Ministry of Education, Chongqing, 400715, China. qiuj318@swu.edu.cn.
6
Department of Psychology, Southwest University, Beibei, Chongqing, 400715, China. qiuj318@swu.edu.cn.

Abstract

Individual differences in the personality trait Agreeableness underlie humans' ability to interpret social cues and coordinate effectively with others. However, previous investigations of the neural basis of Agreeableness have yielded largely inconsistent results. Recent evidence has demonstrated that Agreeableness can be divided into two, correlated subdimensions. Compassion reflects tendencies toward empathy, sympathy, and concern for others, while Politeness reflects tendencies toward compliance and refraining from aggression and exploitation. The present study seeks to clarify the neural substrates of Agreeableness by examining whether structural differences in the brain show distinct associations with Compassion and Politeness. Results of a meta-analysis of fMRI studies examining empathy were used to generate hypotheses about the brain regions and networks that underlie trait Compassion. Results of a large-scale structural neuroimaging investigation (N = 275) were largely consistent with the meta-analysis: Compassion was positively correlated with gray matter volume in the bilateral anterior cingulate cortex (ACC) and anterior insula (AI). Further, these differences appear to be associated with Compassion specifically, as opposed to Politeness, suggesting that these two traits have at least partially distinct neuroanatomical substrates.

KEYWORDS:

Compassion; Empathy; Neuroimaging; Personality

PMID:
28667540
DOI:
10.3758/s13415-017-0529-5
[Indexed for MEDLINE]

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