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J Cancer Res Clin Oncol. 2017 Nov;143(11):2267-2273. doi: 10.1007/s00432-017-2471-x. Epub 2017 Jun 30.

Unmonitored use of herbal medicine by patients with breast cancer: reframing expectations.

Author information

1
Tal Center for Integrative Oncology, Institute of Oncology, Sheba Medical Center, 2 Derech Sheba Road, Tel-Hashomer, 52621, Ramat Gan, Israel. noah.samuels@sheba.health.gov.il.
2
Integrative Oncology Program, Oncology Service and Lin Medical Center, Clalit Health Services, Haifa and Western Galilee District, Haifa, Israel.
3
Complementary and Traditional Medicine Unit, Department of Family Medicine, Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel.
4
Tal Center for Integrative Oncology, Institute of Oncology, Sheba Medical Center, 2 Derech Sheba Road, Tel-Hashomer, 52621, Ramat Gan, Israel.
5
Institute of Oncology, Sheba Medical Center, Tel Hashomer, Israel.

Abstract

PURPOSE:

To identify the unmonitored use of herbal medicine by female patients with breast cancer, examining the impact of an integrative physician (IP) consultation on this practice.

METHODS:

The files of 269 female patients with breast cancer following an IP consultation were surveyed retrospectively for use of herbal medicine for cancer-related goals. Expectations from the IP consultation and adherence to the IP-guided treatments were examined as well.

RESULTS:

Among the cohort, 111 (41.3%) reported using herbal medicine for cancer-related goals, unmonitored by their oncology healthcare professional. Factors predicting herbal medicine use were the adoption of dietary changes (odds ratio = 13.6, p < 0.001, CI 7.16-26.0) and the expectation that the IP consultation and treatments would address cancer-related goals (odds ratio = 3.29, p = 0.001, CI 1.64-6.6). Patients with metastatic disease were more likely to be using herbal medicine than non-users (34.5 vs. 22.8%; p = 0.088), as were those who had consulted with a complementary/alternative medicine practitioner (54.9 vs. 20.8%; p = 0.005). The IP advised 17 patients (15.3%) to stop taking specific herbal products due to safety-related concerns; and 10 patients to take dietary supplements for relief of specific symptoms. Herbal medicine users were less likely than non-users to adhere to the IP-recommended treatment program (34.7 vs. 48.3%; p = 0.037).

CONCLUSIONS:

Unmonitored use of herbal medicine by patients with breast cancer is more frequent among those adopting dietary changes for cancer-related goals. Integrative physicians provide evidence-based guidance on the safe and effective use of herbal products, and reframe patient expectations from cancer-related goals to reducing symptoms and improving quality of life.

KEYWORDS:

Breast cancer; Complementary/integrative medicine; Herbal medicine; Herb–drug interaction; Safety

PMID:
28667389
DOI:
10.1007/s00432-017-2471-x
[Indexed for MEDLINE]

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