THE RELATIONSHIP BETWEEN FOVEAL AVASCULAR ZONE AREA, VESSEL DENSITY, AND CYSTOID CHANGES IN DIABETIC RETINOPATHY: AN OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY STUDY

Retina. 2018 Aug;38(8):1613-1619. doi: 10.1097/IAE.0000000000001755.

Abstract

Purpose: To measure the foveal avascular zone (FAZ) areas and vessel densities of patients with diabetic retinopathy and to study their relationship with diabetic cystoid changes and retinal thickness.

Methods: Prospective case series of 51 eyes of 31 patients with diabetic retinopathy. The eyes were grouped based on the presence or absence of cystoid edema and evaluated using optical coherence tomography angiography. The FAZ areas and vessel density were compared.

Results: The FAZ area at the superficial capillary plexus level was equal between the eyes with and without cystoid edema. Vessel density did not differ as well. There was no correlation with retinal thickness. In eyes with cystoid changes, FAZ area changes at the deep capillary plexus level were difficult to interpret.

Conclusion: The FAZ area and vessel density at the superficial capillary plexus level are reproducible and independent of the presence of cystoid edema.

MeSH terms

  • Aged
  • Diabetic Retinopathy / diagnosis*
  • Diabetic Retinopathy / physiopathology
  • Female
  • Fluorescein Angiography
  • Fovea Centralis / blood supply*
  • Humans
  • Macular Edema / pathology*
  • Male
  • Middle Aged
  • Prospective Studies
  • Retinal Vessels / pathology*
  • Tomography, Optical Coherence / methods