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Curr Rev Musculoskelet Med. 2017 Sep;10(3):346-355. doi: 10.1007/s12178-017-9421-8.

Factors That Affect Outcome Following Total Joint Arthroplasty: a Review of the Recent Literature.

Author information

1
Department of Orthopaedic Surgery, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA, 02115, USA.
2
Department of Orthopaedic Surgery, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA, 02115, USA. jlange1@bwh.harvard.edu.

Abstract

PURPOSE OF REVIEW:

It is well established that certain patient-specific risk factors affect outcomes following total joint arthroplasty. The goal of this paper is to summarize the latest data on several variables that have been investigated in the last 3 years and to characterize the effects these factors have on the success of hip and knee replacement.

RECENT FINDINGS:

Preoperative diagnoses of depression and anxiety, liver disease, hypoalbuminemia, vitamin D deficiency, and diabetes mellitus are associated with increased risk of postoperative complications and can lead to worse outcomes after joint replacement surgery. Recent investigations have clearly established a link between these patient-specific factors and poor outcomes after hip and knee arthroplasty, but future research is needed to determine best practices for stratifying and mitigating these risks for patients.

KEYWORDS:

Depression; Diabetes mellitus; Hypoalbuminemia; Liver disease; Total joint arthroplasty; Vitamin D deficiency

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