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Biomed Opt Express. 2017 Feb 1;8(3):1290-1305. doi: 10.1364/BOE.8.001290. eCollection 2017 Mar 1.

Three-dimensional multi-contrast imaging of in vivo human skin by Jones matrix optical coherence tomography.

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Computational Optics Group, University of Tsukuba, Tennodai 1-1-1, Tsukuba, Ibaraki, 305-8573, Japan.
Computational Optics and Ophthalmology Group, Tsukuba, Ibaraki, Japan.


A custom made dermatological Jones matrix optical coherence tomography (JM-OCT) is presented. It uses a passive-polarization-delay component based swept-source JM-OCT configuration, but is specially designed for in vivo human skin measurement. The center wavelength of its probe beam is 1310 nm and the A-line rate is 49.6 kHz. The JM-OCT is capable of simultaneously providing birefringence (local retardation) tomography, degree-of-polarization-uniformity tomography, complex-correlation-based optical coherence angiography, and conventional scattering OCT. To evaluate the performance of this JM-OCT, we measured in vivo human skin at several locations. Using the four kinds of OCT contrasts, the morphological characteristics and optical properties of different skin types were visualized.


(110.4500) Optical coherence tomography; (110.5405) Polarimetric imaging; (170.1870) Dermatology; (170.4500) Optical coherence tomography

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