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Biomed Opt Express. 2017 Feb 1;8(3):1290-1305. doi: 10.1364/BOE.8.001290. eCollection 2017 Mar 1.

Three-dimensional multi-contrast imaging of in vivo human skin by Jones matrix optical coherence tomography.

Author information

1
Computational Optics Group, University of Tsukuba, Tennodai 1-1-1, Tsukuba, Ibaraki, 305-8573, Japan.
2
Computational Optics and Ophthalmology Group, Tsukuba, Ibaraki, Japan.

Abstract

A custom made dermatological Jones matrix optical coherence tomography (JM-OCT) is presented. It uses a passive-polarization-delay component based swept-source JM-OCT configuration, but is specially designed for in vivo human skin measurement. The center wavelength of its probe beam is 1310 nm and the A-line rate is 49.6 kHz. The JM-OCT is capable of simultaneously providing birefringence (local retardation) tomography, degree-of-polarization-uniformity tomography, complex-correlation-based optical coherence angiography, and conventional scattering OCT. To evaluate the performance of this JM-OCT, we measured in vivo human skin at several locations. Using the four kinds of OCT contrasts, the morphological characteristics and optical properties of different skin types were visualized.

KEYWORDS:

(110.4500) Optical coherence tomography; (110.5405) Polarimetric imaging; (170.1870) Dermatology; (170.4500) Optical coherence tomography

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