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G3 (Bethesda). 2017 Aug 7;7(8):2855-2858. doi: 10.1534/g3.117.043885.

Gene2Function: An Integrated Online Resource for Gene Function Discovery.

Author information

1
Drosophila RNAi Screening Center, Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115.
2
Drosophila RNAi Screening Center, Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115 perrimon@genetics.med.harvard.edu.
3
Biological Laboratories, Harvard University, Cambridge, Massachusetts 02138.
4
Howard Hughes Medical Institute, Boston, Massachusetts 02115.

Abstract

One of the most powerful ways to develop hypotheses regarding the biological functions of conserved genes in a given species, such as humans, is to first look at what is known about their function in another species. Model organism databases and other resources are rich with functional information but difficult to mine. Gene2Function addresses a broad need by integrating information about conserved genes in a single online resource.

KEYWORDS:

data mining; functional genomics; human genetic disease; model organism databases; orthologs

PMID:
28663344
PMCID:
PMC5555488
DOI:
10.1534/g3.117.043885
[Indexed for MEDLINE]
Free PMC Article

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