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Vet Clin North Am Small Anim Pract. 2017 Sep;47(5):1065-1082. doi: 10.1016/j.cvsm.2017.05.001. Epub 2017 Jun 27.

Feline Cardiogenic Arterial Thromboembolism: Prevention and Therapy.

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Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Purdue University, Lynn Hall, 625 Harrison Street, West Lafayette, IN 47907-2026, USA. Electronic address:


Feline cardiogenic arterial thromboembolism (CATE) is a devastating disease whereby 33% of cats survive their initial event, although approximately 50% of mortality is from euthanasia. Short-term management focuses on inducing a hypocoagulable state, improving blood flow, and providing supportive care. Ideally, all cats should be given 72 hours of treatment to determine the acute clinical course. Preventive protocols include antiplatelet and/or anticoagulant drugs, with the only prospective clinical trial demonstrating that clopidogrel is superior to aspirin with a lower CATE recurrence rate and longer time to recurrent CATE. Newer anticoagulant drugs hold great promise in the future of managing this disease.


Cardiac; Cardioembolic; Cat; Feline; Stroke; Thrombosis

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