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J Am Coll Cardiol. 2017 Jul 4;70(1):101-113. doi: 10.1016/j.jacc.2017.05.014.

The Cardiovascular Effects of Cocaine.

Author information

1
Department of Cardiology, Keck School of Medicine, University of Southern California, Los Angeles, California; Department of Cardiology, Tel Aviv Medical Center, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel. Electronic address: Ofer.havakuk@med.usc.edu.
2
Department of Cardiology and Marshfield Clinic Research Institute, Marshfield, Wisconsin.
3
Department of Cardiology, Keck School of Medicine, University of Southern California, Los Angeles, California; Huntington Medical Research Institute, Los Angeles, California. Electronic address: robert.kloner@hmri.org.

Abstract

Cocaine is the leading cause for drug-abuse-related visits to emergency departments, most of which are due to cardiovascular complaints. Through its diverse pathophysiological mechanisms, cocaine exerts various adverse effects on the cardiovascular system, many times with grave results. Described here are the varied cardiovascular effects of cocaine, areas of controversy, and therapeutic options.

KEYWORDS:

acute myocardial infarction; beta-blockers; cardiomyopathy; cocaine cardiotoxicity; drug addiction

PMID:
28662796
DOI:
10.1016/j.jacc.2017.05.014
[Indexed for MEDLINE]
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