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Crit Rev Food Sci Nutr. 2018;58(16):2790-2799. doi: 10.1080/10408398.2017.1341865. Epub 2017 Aug 21.

The emerging role of curcumin for improving vascular dysfunction: A review.

Author information

1
a Department of Kinesiology and Health Promotion , University of Kentucky , Lexington , Kentucky , United States.

Abstract

Curcumin, when administered in a bioavailable form, has potential to influence vascular health of various populations, leading to decreases in cardiovascular disease risk. Clinical intervention studies with curcumin have demonstrated significant improvements in endothelial function, arterial compliance, arterial stiffness, and other measures of vascular hemodynamics in young, middle-aged, old, post-menopausal, healthy, diabetic, and obese individuals. Mechanistically, curcumin is believed to improve vascular function through its effects on inflammation, oxidative stress, nitric oxide bioavailability, and structural proteins of the artery. Current data give support for curcumin to be administered for improvements in vascular health to individuals that may or may not be at risk for cardiovascular disease. This review briefly summarizes the techniques used for the establishment of vascular health and overviews the literature investigating the role of curcumin in the improvement of vascular health.

KEYWORDS:

Turmeric; arterial stiffness; bioavailability; endothelial function; inflammation; oxidative stress

PMID:
28662351
DOI:
10.1080/10408398.2017.1341865
[Indexed for MEDLINE]

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