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Breast Dis. 2017;37(2):63-68. doi: 10.3233/BD-160244.

The overall 5-year survival rate of breast cancer among Iranian women: A systematic review and meta-analysis of published studies.

Author information

1
Research Center for Health Sciences, Shiraz University of Medical Sciences, Shiraz, Iran.
2
Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran.

Abstract

INTRODUCTION:

Breast Cancer (BC) is the most prevalent cancer and the second leading cause of cancer-related death among Iranian women. A valid estimation of the 5-year survival rate can improve the current BC treatment programs. The present study aimed to assess the 5-year survival rate through a systematic review of published studies.

METHODS:

A systematic search of Medline/PubMed, Scopus, and Science direct as well as Iranian databases was conducted to identify the original articles evaluating the 5-year survival rate of BC among women in Iran. Random effects model was used to estimate the pooled 5-year survival rate. The eligible articles were analyzed using the Stata software.

RESULTS:

Our comprehensive literature search identified 11 eligible articles 2 of which were excluded due to reporting the results of a single study. The remaining 9 articles that contained 4815 women diagnosed with BC during 1991-2014 were included in the meta-analysis. The combined 5-year survival rate of BC was estimated to be 67.60%.

DISCUSSION/CONCLUSION:

The survival rate of BC was relatively low in Iran compared to developed countries. Hence, more effective measures have to be taken to increase these patients' survival.

KEYWORDS:

Iran; Survival rate; breast cancer; meta-analysis; systematic review

PMID:
28655117
DOI:
10.3233/BD-160244
[Indexed for MEDLINE]

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