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F1000Res. 2017 May 26;6:750. doi: 10.12688/f1000research.11120.1. eCollection 2017.

Leishmaniasis: a review.

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1
Sección de Micología, Hospital "Manuel Gea González" Secretaría de Salud, Calz. de Tlalpan 4800, Ciudad de México 14080, Mexico.
2
Dermatólogo, Clínica Carranza, Chetumal, Quintana Roo, Mexico.

Abstract

Leishmaniasis is caused by an intracellular parasite transmitted to humans by the bite of a sand fly. It is endemic in Asia, Africa, the Americas, and the Mediterranean region. Worldwide, 1.5 to 2 million new cases occur each year, 350 million are at risk of acquiring the disease, and leishmaniasis causes 70,000 deaths per year. Clinical features depend on the species of Leishmania involved and the immune response of the host. Manifestations range from the localized cutaneous to the visceral form with potentially fatal outcomes. Many drugs are used in its treatment, but the only effective treatment is achieved with current pentavalent antimonials.

KEYWORDS:

Leishmania; Leishmaniasis; chicleros ulcer; cutaneous-chondral

Conflict of interest statement

Competing interests: The authors declare that they have no competing interests.No competing interests were disclosed.No competing interests were disclosed.

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