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J Cancer Res Ther. 2017 Apr-Jun;13(2):193-197. doi: 10.4103/0973-1482.189234.

Thrombocytosis in gynecological cancers.

Author information

1
Department of Radiation Oncology, VMMC and Safdarjung Hospital, New Delhi, India.

Abstract

Thrombocytosis has been suggested to be a poor prognostic indicator in malignancies. Studies have shown that thrombocytosis is associated with a poor prognosis in various gynecological malignancies such as carcinoma ovary, cervical cancer, and endometrial cancer. The aim of this study is to analyze the impact of thrombocytosis on the prognosis of gynecological cancer. All the relevant data were retrieved by PubMed, MEDLINE, and Web of Science, and then studies were chosen in this analysis of association between thrombocytosis and gynecological malignancy. Thrombocytosis is common in advanced disease in patients with ovarian cancer, endometrial cancer, and cervical cancer. Therefore, it may be a marker of tumor burden or biologically more aggressive disease. Thrombocytosis is bad prognostic factor and associated with poorer outcomes.

PMID:
28643732
DOI:
10.4103/0973-1482.189234
[Indexed for MEDLINE]
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