Format

Send to

Choose Destination
Medicine (Baltimore). 2017 Jun;96(25):e7174. doi: 10.1097/MD.0000000000007174.

Effect of transforaminal epidural polydeoxyribonucleotide injections on lumbosacral radiculopathy: A case report.

Author information

1
aDepartment of Anesthesiology and Pain Medicine, National Police Hospital, Seoul bDepartment of Orthopaedic Surgery, Changwon Gyeongsang National University Hospital cDepartment of Anesthesiology and Pain Medicine, Catholic Kwandong University of Korea College of Medicine, International St. Mary's Hospital, Incheon, Republic of Korea.

Abstract

RATIONALE:

Transforaminal epidural glucocorticoids administration is widely performed for the management of lumbosacral radiculopathy. However, it may worsen the condition of patients with type 2 diabetes mellitus (DM). Polydeoxyribonucleotide (PDRN) was recently noted as a substitute for glucocorticoids.

PATIENT CONCERNS:

A 44-year-old male patient was admitted to our pain clinic with symptoms of low back pain with severe pain and tingling sensation of left posterolateral leg. He had type 2 DM medicated with Glimepiride and Metformin. Blood glucose level was 367 mg/dL. He declined to use glucocorticoid.

DIAGNOSES:

He was diagnosed as left foraminal disc protrusion at L4-5, left subarticular disc protrusion at L5-S1.

INTERVENTIONS:

Fluoroscopically guided transforaminal epidural PDRN injections were carried out.

OUTCOMES:

The patient was followed up for more than 6 months and demonstrated good improvement in lumbosacral radiculopathy without any complications.

LESSONS:

This is the first successful report on epidural injection of PDRN.

PMID:
28640096
PMCID:
PMC5484204
DOI:
10.1097/MD.0000000000007174
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for Wolters Kluwer Icon for PubMed Central
Loading ...
Support Center