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Am J Psychiatry. 1985 Oct;142(10):1137-45.

Neuroleptic malignant syndrome.

Abstract

Neuroleptic malignant syndrome is a rare but serious adverse effect of antipsychotic medication. The author describes three new cases and reviews 50 others published in the past 5 years. Demographic and clinical features, diagnosis, treatment, outcome, and pathophysiology are critically reviewed, and a new set of diagnostic criteria, incorporating physical signs and routine laboratory tests, is proposed.

PMID:
2863986
DOI:
10.1176/ajp.142.10.1137
[Indexed for MEDLINE]

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