Send to

Choose Destination
Implement Sci. 2017 Jun 21;12(1):77. doi: 10.1186/s13012-017-0605-9.

A guide to using the Theoretical Domains Framework of behaviour change to investigate implementation problems.

Author information

Centre for Behaviour Change, University College London, London, UK.
School of Health Sciences City, University of London, London, UK.
Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Canada.
School of Public Health and Preventative Medicine, Monash University, Melbourne, VIC, Australia.
Women's College Research Institute, Women's College Hospital and Department of Family and Community Medicine, University of Toronto, Toronto, Canada.
Leeds Institute of Health Sciences, University of Leeds, Leeds, UK.
Health Services Research Unit, University of Aberdeen, Aberdeen, UK.
Department of Occupational Science and Occupational Therapy, University of Toronto, Toronto, Canada.
Department of Medicine, University of Ottawa, Ottawa, Canada.
Institute of Psychological Sciences, University of Leeds, Leeds, UK.
Centre for Behaviour Change, University College London, London, UK.



Implementing new practices requires changes in the behaviour of relevant actors, and this is facilitated by understanding of the determinants of current and desired behaviours. The Theoretical Domains Framework (TDF) was developed by a collaboration of behavioural scientists and implementation researchers who identified theories relevant to implementation and grouped constructs from these theories into domains. The collaboration aimed to provide a comprehensive, theory-informed approach to identify determinants of behaviour. The first version was published in 2005, and a subsequent version following a validation exercise was published in 2012. This guide offers practical guidance for those who wish to apply the TDF to assess implementation problems and support intervention design. It presents a brief rationale for using a theoretical approach to investigate and address implementation problems, summarises the TDF and its development, and describes how to apply the TDF to achieve implementation objectives. Examples from the implementation research literature are presented to illustrate relevant methods and practical considerations.


Researchers from Canada, the UK and Australia attended a 3-day meeting in December 2012 to build an international collaboration among researchers and decision-makers interested in the advancing use of the TDF. The participants were experienced in using the TDF to assess implementation problems, design interventions, and/or understand change processes. This guide is an output of the meeting and also draws on the authors' collective experience. Examples from the implementation research literature judged by authors to be representative of specific applications of the TDF are included in this guide.


We explain and illustrate methods, with a focus on qualitative approaches, for selecting and specifying target behaviours key to implementation, selecting the study design, deciding the sampling strategy, developing study materials, collecting and analysing data, and reporting findings of TDF-based studies. Areas for development include methods for triangulating data, e.g. from interviews, questionnaires and observation and methods for designing interventions based on TDF-based problem analysis.


We offer this guide to the implementation community to assist in the application of the TDF to achieve implementation objectives. Benefits of using the TDF include the provision of a theoretical basis for implementation studies, good coverage of potential reasons for slow diffusion of evidence into practice and a method for progressing from theory-based investigation to intervention.


Guide; Methods; Theoretical Domains Framework

[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for BioMed Central Icon for PubMed Central
Loading ...
Support Center