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Biosensors (Basel). 2017 Jun 21;7(2). pii: E23. doi: 10.3390/bios7020023.

Towards a Uniform Metrological Assessment of Grating-Based Optical Fiber Sensors: From Refractometers to Biosensors.

Author information

1
Institute of Applied Physics "Nello Carrara", IFAC-CNR, Via Madonna del Piano 10, 50019 Sesto Fiorentino, Italy. f.chiavaioli@ifac.cnr.it.
2
Institute for Systems and Computer Engineering, Technology and Science, INESC-TEC, Rua do Campo Alegre 687, Porto 4169-007, Portugal. icarlos07@gmail.com.
3
Institute INESC P&D Brasil, Rua José Caballero, 15, Gonzaga, 11055-300 Santos, Brazil. icarlos07@gmail.com.
4
Institute for Systems and Computer Engineering, Technology and Science, INESC-TEC, Rua do Campo Alegre 687, Porto 4169-007, Portugal. pedro.jorge@inesctec.pt.
5
Institute of Applied Physics "Nello Carrara", IFAC-CNR, Via Madonna del Piano 10, 50019 Sesto Fiorentino, Italy. f.baldini@ifac.cnr.it.

Abstract

A metrological assessment of grating-based optical fiber sensors is proposed with the aim of providing an objective evaluation of the performance of this sensor category. Attention was focused on the most common parameters, used to describe the performance of both optical refractometers and biosensors, which encompassed sensitivity, with a distinction between volume or bulk sensitivity and surface sensitivity, resolution, response time, limit of detection, specificity (or selectivity), reusability (or regenerability) and some other parameters of generic interest, such as measurement uncertainty, accuracy, precision, stability, drift, repeatability and reproducibility. Clearly, the concepts discussed here can also be applied to any resonance-based sensor, thus providing the basis for an easier and direct performance comparison of a great number of sensors published in the literature up to now. In addition, common mistakes present in the literature made for the evaluation of sensor performance are highlighted, and lastly a uniform performance assessment is discussed and provided. Finally, some design strategies will be proposed to develop a grating-based optical fiber sensing scheme with improved performance.

KEYWORDS:

biosensor; fiber Bragg grating; limit of detection; long period grating; optical fiber grating; refractive index sensor; resolution; resonance-based device; sensitivity; specificity

PMID:
28635665
PMCID:
PMC5487959
DOI:
10.3390/bios7020023
[Indexed for MEDLINE]
Free PMC Article

Conflict of interest statement

The authors declare no conflict of interest. The founding sponsors had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript, nor in the decision to publish the results.

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