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J Allergy Clin Immunol. 2017 Nov;140(5):1461-1464.e8. doi: 10.1016/j.jaci.2017.04.048. Epub 2017 Jun 17.

Mitochondrial DNA depletion induces innate immune dysfunction rescued by IFN-γ.

Author information

1
Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom; Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom.
2
Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom; Medical Research Council Mitochondrial Biology Unit, Cambridge Biomedical Campus, Cambridge, United Kingdom.
3
Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom; Bioinformatics Support Unit, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom.
4
Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom.
5
Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom.
6
Department of Anaesthesia, Royal Victoria Infirmary, Newcastle upon Tyne, United Kingdom.
7
Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom. Electronic address: j.simpson@ncl.ac.uk.
8
Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom; Medical Research Council Mitochondrial Biology Unit, Cambridge Biomedical Campus, Cambridge, United Kingdom; Department of Clinical Neurosciences, University of Cambridge, Cambridge, United Kingdom. Electronic address: pfc25@cam.ac.uk.
PMID:
28629747
PMCID:
PMC5667580
DOI:
10.1016/j.jaci.2017.04.048
[Indexed for MEDLINE]
Free PMC Article

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