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J Matern Fetal Neonatal Med. 2018 Jul;31(13):1798-1806. doi: 10.1080/14767058.2017.1326904. Epub 2017 Jun 18.

Maternal autoimmune disorders and fetal defects.

Author information

1
a Fetal Medicine Research Institute , King's College Hospital , London , UK.

Abstract

Maternal autoantibodies can cross the placenta and cause fetal damage. This article summarizes the development and management of fetal thyroid goiter in response to maternal Graves' disease and/or its treatment with antithyroid medication, fetal heart block due to maternal anti-Ro and anti-La antibodies, fetal athrogryposis multiplex congenita in association with maternal myasthenia gravis and fetal brain hemorrhage due to maternal autoimmune thrombocytopenia.

KEYWORDS:

Graves’ disease; Maternal autoantibodies; anti-Ro and anti-La antibodies; athrogryposis multiplex congenital; autoimmune thrombocytopenia; fetal brain hemorrhage; fetal heart block; fetal thyroid goiter; myasthenia gravis

PMID:
28627279
DOI:
10.1080/14767058.2017.1326904
[Indexed for MEDLINE]

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