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Lung Cancer. 2017 Jun;108:140-149. doi: 10.1016/j.lungcan.2017.03.014. Epub 2017 Mar 30.

Lung cancer incidence trends in California by race/ethnicity, histology, sex, and neighborhood socioeconomic status: An analysis spanning 28 years.

Author information

1
Division of Oncology, Department of Medicine, Stanford University School of Medicine, 875 Blake Wilbur Drive, Stanford, CA, 94305, USA; Primary Care and Outcomes Research, Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA. Electronic address: manalip@stanford.edu.
2
Cancer Prevention Institute of California, 2201 Walnut Avenue, Fremont, CA, 94538, USA.
3
Stanford Cancer Institute, 875 Blake Wilbur Drive, Stanford, CA, 94305, USA.
4
Division of Oncology, Department of Medicine, Stanford University School of Medicine, 875 Blake Wilbur Drive, Stanford, CA, 94305, USA; Stanford Cancer Institute, 875 Blake Wilbur Drive, Stanford, CA, 94305, USA.
5
Cancer Prevention Institute of California, 2201 Walnut Avenue, Fremont, CA, 94538, USA; Stanford Cancer Institute, 875 Blake Wilbur Drive, Stanford, CA, 94305, USA.

Abstract

OBJECTIVES:

Lung cancer incidence trends by histology, sex, race/ethnicity, and neighborhood socioeconomic status (nSES) have not been previously reported. We conducted a population-based study of lung cancer incidence over three peri-censal periods: 1988-1992, 1998-2002, and 2008-2012.

MATERIALS AND METHODS:

We abstracted lung cancer cases from the California Cancer Registry and used US Census and American Community Survey data to develop multidimensional nSES indices for each census period. We calculated nSES tertile-specific incidence rates and rate ratios for each peri-censal period and used incidence rate ratios (IRR) to assess changes in rates from 1988 to 1992 to 1998-2002 and 2008-2012.

RESULTS:

There were a total of 231,205 lung cancer cases. Males: Among males, incidence rates of lung cancer decreased over time, all race/ethnicities, and all nSES tertiles, with larger declines among males in higher nSES areas. Rates either declined or were stable for adenocarcinoma, with larger declines for other histologic subtypes. Females: Among females, declines in incidence rates of lung cancer were more pronounced for females in higher nSES areas, but diverged more so than for males, with variations by histology and race/ethnicity. Incidence rates of adenocarcinoma increased over time among all females, with greater increase among females in low nSES areas.

CONCLUSIONS:

Our findings demonstrate differences in incidence trends over three decades by histology, gender, race/ethnicity, and nSES. While incidence rates consistently declined over time for males, there were greater declines in incidence for high nSES populations. In contrast, among females, there was evidence of increases in lung cancer incidence among low SES API females, and for adenocarcinoma.

KEYWORDS:

Health status disparities; Histology; Incidence; Incidence trends; Lung cancer; Racial/ethnic disparities; Socioeconomic status

PMID:
28625626
DOI:
10.1016/j.lungcan.2017.03.014
[Indexed for MEDLINE]

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