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J Am Acad Dermatol. 2017 Jul;77(1):17-29. doi: 10.1016/j.jaad.2016.11.010.

Current and emerging treatments for vitiligo.

Author information

1
Department of Dermatology, St. Vincent's Hospital, The Skin and Cancer Foundation Inc, Victoria, Australia; The Royal Children's Hospital, Victoria, Australia. Electronic address: dr.rodrigues@gmail.com.
2
Department of Dermatology, Henri Mondor Hospital, Creteil, France; EpiDermE, Universite Paris-Est, Creteil, France.
3
Department of Dermatology, Henry Ford Hospital, Detroit, Michigan.
4
Department of Dermatology, University of Texas Southwestern Medical Center, Dallas, Texas.
5
Department of Dermatology, University of Massachusetts Medical School, Worcester, Massachusetts.

Abstract

Clinicians should be aware that vitiligo is not merely a cosmetic disease and that there are safe and effective treatments available for vitiligo. It is important to recognize common and uncommon presentations and those with active disease, as well as their implications for clinical management; these were discussed in the first article in this continuing medical education series. Existing treatments include topical and systemic immunosuppressants, phototherapy, and surgical techniques, which together may serve to halt disease progression, stabilize depigmented lesions, and encourage repigmentation. We discuss how to optimize the currently available treatments and highlight emerging treatments that may improve treatment efficacy in the future.

KEYWORDS:

afamelanotide; biologics; corticosteroids; excimer lamp; excimer laser; grafting; leukoderma; methotrexate; narrowband ultraviolet light; phototherapy; pigmentation; tacrolimus; treatment; vitiligo

PMID:
28619557
DOI:
10.1016/j.jaad.2016.11.010
[Indexed for MEDLINE]
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