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Trends Microbiol. 2017 Jun 10. pii: S0966-842X(17)30132-4. doi: 10.1016/j.tim.2017.05.014. [Epub ahead of print]

A Single Substitution Changes Zika Virus Infectivity in Mosquitoes.

Author information

1
Jiangsu Key Laboratory for Microbes and Functional Genomics, Jiangsu Engineering and Technology Research Center for Microbiology, College of Life Sciences, Nanjing Normal University, Nanjing, Jiangsu 210046, China
. Electronic address: guanzhu@njnu.edu.cn.

Abstract

Zika virus (ZIKV) has caused outbreaks in the Pacific and the Americas. The mechanism underlying the recent ZIKV epidemic remains obscure. A recent study reveals that an amino acid substitution is associated with increased infectivity of ZIKV in the Aedes aegypti mosquito.

KEYWORDS:

Zika virus; amino acid substitution; transmission vector

PMID:
28610876
DOI:
10.1016/j.tim.2017.05.014
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