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Ann Otol Rhinol Laryngol. 2017 Jul;126(7):544-547. doi: 10.1177/0003489417708794.

Volumetric Growth Rate of Recurrent Pleomorphic Adenoma.

Author information

1
1 Department of Otolaryngology-Head and Neck Surgery, University of California-San Francisco Medical Center, San Francisco, California, USA.
2
2 Department of Radiology and Biomedical Imaging, Division of Neuroradiology, University of California-San Francisco Medical Center, San Francisco, California, USA.
3
3 Division of Head and Neck Oncologic Surgery, Department of Otolaryngology-Head and Neck Surgery, University of California-San Francisco Medical Center, San Francisco, California, USA.
4
4 Department of Otolaryngology-Head and Neck Surgery, University of Arizona College of Medicine, Tuscon, Arizona, USA.

Abstract

OBJECTIVES:

Surgery for recurrent pleomorphic adenoma (PA) can be challenging and may increase the risk of operative complications, particularly facial nerve weakness. As observation may be a viable alternative to surgery for slow-growing tumors, our objective was to assess the growth rate of recurrent PAs.

STUDY DESIGN:

This study is a case series of patients at our tertiary academic medical center with recurrent PA. Two magnetic resonance images (MRI) were compared; total volume (TV) of recurrent tumor on both studies was calculated to obtain our main outcomes of percent change in TV and tumor growth rate.

RESULTS:

Fourteen patients with recurrent PA had a median interval time between MRI of 12.8 months. Though growth rates were variable, the median continuous compound growth per year was 10.2%. Notably, 3 patients (21%) had no growth, and 2 patients (14%) had a reduction in TV.

CONCLUSIONS:

The median growth rate for enlarging tumors is estimated at 10.2% per year. Due to variability, tumor growth rate should be estimated on an individual patient basis. For slow-growing tumors, physicians may weigh the risk of this slow growth with the morbidity of reoperation.

KEYWORDS:

imaging; recurrent pleomorphic adenoma; surveillance

PMID:
28604082
DOI:
10.1177/0003489417708794
[Indexed for MEDLINE]

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