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Prog Biophys Mol Biol. 2017 Dec;131:193-212. doi: 10.1016/j.pbiomolbio.2017.05.014. Epub 2017 Jun 8.

Some resonances between Eastern thought and Integral Biomathics in the framework of the WLIMES formalism for modeling living systems.

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Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, Berlin, Germany; Dahlem Centre for Genome Research and Medical Systems Biology, Berlin, Germany; JSRC, Berlin, Germany. Electronic address:
Université de Picardie Jules Verne, LAMFA, Amiens, France.


Forty-two years ago, Capra published "The Tao of Physics" (Capra, 1975). In this book (page 17) he writes: "The exploration of the atomic and subatomic world in the twentieth century has …. necessitated a radical revision of many of our basic concepts" and that, unlike 'classical' physics, the sub-atomic and quantum "modern physics" shows resonances with Eastern thoughts and "leads us to a view of the world which is very similar to the views held by mystics of all ages and traditions." This article stresses an analogous situation in biology with respect to a new theoretical approach for studying living systems, Integral Biomathics (IB), which also exhibits some resonances with Eastern thought. Stepping on earlier research in cybernetics1 and theoretical biology,2 IB has been developed since 2011 by over 100 scientists from a number of disciplines who have been exploring a substantial set of theoretical frameworks. From that effort, the need for a robust core model utilizing advanced mathematics and computation adequate for understanding the behavior of organisms as dynamic wholes was identified. At this end, the authors of this article have proposed WLIMES (Ehresmann and Simeonov, 2012), a formal theory for modeling living systems integrating both the Memory Evolutive Systems (Ehresmann and Vanbremeersch, 2007) and the Wandering Logic Intelligence (Simeonov, 2002b). Its principles will be recalled here with respect to their resonances to Eastern thought.


Artificial/synthetic and natural life; Eastern philosophy; Higher-order logic; Integral Biomathics; Memory Evolutive Systems; Phenomenology; Wandering Logic Intelligence

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