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Pharmacogenomics. 2017 Jun;18(9):835-841. doi: 10.2217/pgs-2017-0042. Epub 2017 Jun 8.

Clinical and educational impact of pharmacogenomics testing: a case series from the INGENIOUS trial.

Author information

1
Department of Obstetrics, Gynecology & Women's Health, University of Louisville, KY 40202, USA.
2
Department of Medicine, Division of Clinical Pharmacology, Indiana University, IN 46202, USA.
3
Department of Medicine, Division of Nephrology, Indiana University, IN 46202, USA.

Abstract

Pharmacogenomic testing has become increasingly widespread. However, there remains a need to bridge the gap between test results and providers lacking the expertise required to interpret these results. The Indiana Genomics Implementation trial is underway at our institution to examine total healthcare cost and patient outcomes after genotyping in a safety-net healthcare system. As part of the study, trial investigators and clinical pharmacology fellows interpret genotype results, review patient histories and medication lists and evaluate potential drug-drug interactions. We present a case series of patients in whom pharmacogenomic consultations aided providers in appropriately applying pharmacogenomic results within the clinical context. Formal consultations not only provide valuable patient care information but educational opportunities for the fellows to cement pharmacogenomic concepts.

KEYWORDS:

education; genetic testing; pharmacogenetics; pharmacology; precision medicine;  clinical

PMID:
28594278
PMCID:
PMC5591461
DOI:
10.2217/pgs-2017-0042
[Indexed for MEDLINE]
Free PMC Article

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