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Lancet Oncol. 2017 Jun;18(6):e330-e340. doi: 10.1016/S1470-2045(17)30345-5.

European Association for Neuro-Oncology (EANO) guidelines for palliative care in adults with glioma.

Author information

1
Neuro-Oncology Unit, Regina Elena Cancer Institute, Rome, Italy.
2
Department of Neurology, Leiden University Medical Center, Leiden, Netherlands; Department of Neurology, Haaglanden Medical Center, The Hague, Netherlands.
3
Department of Palliative Medicine, University Hospital of Cologne, Cologne, Germany.
4
Department of Palliative Medicine, University Hospital Waterford, Waterford, Ireland.
5
Department of Neuro-Oncology, University and City of Health and Science Hospital, Turin, Italy.
6
Department of Internal Medicine I, Clinical Division of Medical Oncology, Medical University of Vienna, Vienna, Austria.
7
Neuro-Oncology Unit, Department of Neurosurgery, University Hospital, Lille, France; Breast Unit, Department of Medical Oncology, Oscar Lambret Center, Lille, France.
8
Edinburgh Centre for Neuro-Oncology, Western General Hospital, Edinburgh, UK.
9
International Brain Tumour Alliance, Tadworth, UK.
10
Department of Neuroscience, Cambridge University Hospitals, Cambridge, UK.
11
brainstrust, Cowes, Isle of Wight, UK.
12
Division of Psychiatry, University of Edinburgh, Royal Edinburgh Hospital, Edinburgh, UK.
13
Regional Cancer Center Stockholm Gotland, Stockholm, Sweden; Department of Radiation Sciences and Oncology, Umeå University, Umeå, Sweden.
14
Amsterdam Public Health Research Institute, Department of Public and Occupational Health, VU University Medical Center, Amsterdam, Netherlands.
15
Department of Neurology, University Clinic St Pölten, Karl Landsteiner Private University and Karl Landsteiner Institute for Neurology and Neuropsychology, St Pölten, Austria.
16
Department of Neurology, University Hospital, University of Zurich, Zurich, Switzerland.
17
Department of Neurology, Leiden University Medical Center, Leiden, Netherlands; Department of Neurology, Haaglanden Medical Center, The Hague, Netherlands. Electronic address: m.taphoorn@haaglandenmc.nl.

Abstract

Patients with glioma present with complex palliative care needs throughout their disease trajectory. The life-limiting nature of gliomas and the presence of specific symptoms related to neurological deterioration necessitate an appropriate and early palliative care approach. The multidisciplinary palliative care task force of the European Association of Neuro-Oncology did a systematic review of the available scientific literature to formulate the best possible evidence-based recommendations for the palliative care of adult patients with glioma, with the aim to reduce symptom burden and improve the quality of life of patients and their caregivers, particularly in the end-of-life phase. When recommendations could not be made because of the scarcity of evidence, the task force either used evidence from studies of patients with systemic cancer or formulated expert opinion. Areas of palliative care that currently lack evidence and thus deserve attention for further research are fatigue, disorders of behaviour and mood, interventions for the needs of caregivers, and timing of advance care planning.

PMID:
28593859
DOI:
10.1016/S1470-2045(17)30345-5
[Indexed for MEDLINE]
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