Format

Send to

Choose Destination
Pharmacogenomics. 2017 Jun;18(8):773-785. doi: 10.2217/pgs-2017-0027. Epub 2017 Jun 8.

The experience of physicians in pharmacogenomic clinical decision support within eight German university hospitals.

Author information

1
Chair of Medical Informatics, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.
2
Faculty of Medicine & Medical Center, Institute of Medical Biometry & Statistics, University of Freiburg, Freiburg, Germany.
3
Department of Medicine, Hematology/Oncology, Goethe University, Frankfurt, Germany.
4
Institute of Medical Biostatistics, Epidemiology & Informatics (IMBEI), University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany.
5
Department of Medical Informatics, Division of Translational Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
6
Medical Directorate, University Hospital Magdeburg, Magdeburg, Germany.
7
Medical Faculty Mannheim, Institute for Clinical Chemistry, Ruprecht-Karls-University Heidelberg, Mannheim, Germany.
8
Coordinating Centre for Clinical Trials, Philipps University Marburg, Marburg, Germany.
9
Institute of Neuropathology, University of Giessen, Giessen, Germany.

Abstract

AIM:

The aim of this study was to assess the physicians' attitude, their knowledge and their experience in pharmacogenomic clinical decision support in German hospitals.

MATERIALS & METHODS:

We conducted an online survey to address physicians of 13 different medical specialties across eight German university hospitals. In total, 564 returned questionnaires were analyzed.

RESULTS:

The remaining knowledge gap, the uncertainty of test reimbursement and the physicians' lack of awareness of existing pharmacogenomic clinical decision support systems (CDSS) are the major barriers for implementing pharmacogenomic CDSS into German hospitals. Furthermore, pharmacogenomic CDSS are most effective in the form of real-time decision support for internists.

CONCLUSION:

Physicians in German hospitals require additional education of both genetics and pharmacogenomics. They need to be provided with access to relevant pharmacogenomic CDSS.

KEYWORDS:

German university hospital; clinical decision support; pharmacogenomic

PMID:
28593816
DOI:
10.2217/pgs-2017-0027
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Atypon
Loading ...
Support Center