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Am J Clin Nutr. 2017 Jul;106(1):162-167. doi: 10.3945/ajcn.117.154872. Epub 2017 Jun 7.

Fried potato consumption is associated with elevated mortality: an 8-y longitudinal cohort study.

Author information

National Research Council, Aging Branch, Neuroscience Institute, Padua, Italy.
Institute for Clinical Research and Education in Medicine, Padua, Italy.
Physiotherapy Department, South London.
Maudsley NHS Foundation Trust, London, United Kingdom.
Health Service and Population Research Department, Institute of Psychiatry, Psychology, and Neuroscience, King's College London, London, United Kingdom.
Faculty of Health, Social Care, and Education, Anglia Ruskin University, Chelmsford, United Kingdom.
Institute for Clinical Research and Education in Medicine, Padua, Italy;
Department of Neurosciences, University of Padua, Padua, Italy.
Primary Care Department, Azienda Local Health Unit (ULSS) 20 Verona, Verona, Italy.
Primary Care Department, Azienda USL Toscana Sud Est, Grosseto, Italy.
Local Health Services Unit, Azienda Social and Health Unit (APSS) Trento, Trento, Italy.
Research and Development Unit, Parc Sanitari Sant Joan de Déu, Fundació Sant Joan de Déu, CIBERSAM, Barcelona, Spain.
Department of Clinical and Experimental Sciences, Brescia University Medical School, Brescia, Italy;
CEINGE Biotecnologie Avanzate, Naples, Italy; and.
Division of Geriatrics and Nutritional Science, Washington University, St. Louis, MO.


Background: Few studies have assessed the association between potato consumption and mortality.Objective: We investigated whether potato consumption (including fried and unfried potatoes) is associated with increased premature mortality risk in a North American cohort.Design: A longitudinal analysis included 4440 participants aged 45-79 y at baseline with an 8-y follow-up from the Osteoarthritis Initiative cohort study. Potato consumption (including fried and unfried potatoes) was analyzed by using a Block Brief 2000 food-frequency questionnaire and categorized as ≤1 time/mo, 2-3 times/mo, 1 time/wk, 2 times/wk, or ≥3 times/wk. Mortality was ascertained through validated cases of death. To investigate the association between potato consumption and mortality, Cox regression models were constructed to estimate HRs with 95% CIs, with adjustment for potential confounders.Results: Of the 4400 participants, 2551 (57.9%) were women with a mean ± SD age of 61.3 ± 9.2 y. During the 8-y follow-up, 236 participants died. After adjustment for 14 potential baseline confounders, and taking those with the lowest consumption of potatoes as the reference group, participants with the highest consumption of potatoes did not show an increased risk of overall mortality (HR: 1.11; 95% CI: 0.65, 1.91). However, subgroup analyses indicated that participants who consumed fried potatoes 2-3 times/wk (HR: 1.95; 95% CI: 1.11, 3.41) and ≥3 times/wk (HR: 2.26; 95% CI: 1.15, 4.47) were at an increased risk of mortality. The consumption of unfried potatoes was not associated with an increased mortality risk.Conclusions: The frequent consumption of fried potatoes appears to be associated with an increased mortality risk. Additional studies in larger sample sizes should be performed to confirm if overall potato consumption is associated with higher mortality risk. This trial was registered at as NCT00080171.


Osteoarthritis Initiative.; mortality; potato; risk factor

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