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Australas J Dermatol. 2017 Nov;58(4):286-291. doi: 10.1111/ajd.12595. Epub 2017 Jun 7.

Lentigo maligna of the face: A quantitative simple method to identify individual patient risk probability on dermoscopy.

Author information

1
Department of Oncological and Preventative Dermatological, San Gallicano Dermatological Institute, IRCCS, Rome, Italy.
2
Department of Dermatology, Clinica Dermatologica, La Sapienza University of Rome, Rome, Italy.
3
Department of Biostatistics, Regina Elena National Cancer Institute, Rome, Italy.

Abstract

BACKGROUND/OBJECTIVES:

The clinical and dermoscopic differential diagnosis of flat pigmented facial lesions represents a great challenge for the clinicians. Our aim was to report a quantitative method based on dermoscopic features to better classify pigmented facial lesions.

METHODS:

This is a retrospective case-series study that analysed the dermoscopic features of 582 pigmented facial lesions.

RESULTS:

The individual patient probability of lentigo maligna (LM) was predicted by a multivariate model, with an accuracy of 0.72. According to the odds ratio at the multivariate analysis, an individual scoring index was assigned to each criterion, and a value of 4.56 was identified as optimal cut-off point. Up to a score of 2.5, the probability that a lesion is an LM is 0. The probability increases from 10 to 50% for a score ranging between 4.5 and 6. It is about 90% for a score of 7.

CONCLUSION:

The optimal cut-off point obtained and the curve that identifies the probability of a patient having a LM could improve the classification and the management strategies of equivocal pigmented facial lesions.

KEYWORDS:

dermoscopy; lentigo maligna; lichen planus-like keratosis; pigmented actinic keratosis; pigmented facial lesions; solar lentigo

PMID:
28589538
DOI:
10.1111/ajd.12595
[Indexed for MEDLINE]

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