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Indian J Gastroenterol. 2017 May;36(3):179-183. doi: 10.1007/s12664-017-0750-8. Epub 2017 Jun 7.

Prevalence of abnormal lactose breath hydrogen tests in children with functional abdominal pain.

Author information

1
Department of Pediatrics, Lady Hardinge Medical College, C-604, Shaheed Bhagat Singh Road, Diz Area, Connaught Place, New Delhi, 110 001, India.
2
Department of Pediatrics, Lady Hardinge Medical College, C-604, Shaheed Bhagat Singh Road, Diz Area, Connaught Place, New Delhi, 110 001, India. pkpaed@gmail.com.

Abstract

OBJECTIVES:

The study was undertaken to determine the prevalence of abnormal lactose breath hydrogen test in children with non-organic chronic abdominal pain.

METHODS:

Children with chronic abdominal pain were examined and investigated for organic causes. All children without a known organic cause underwent lactose and glucose breath hydrogen test. After a standard dose of 2 g/kg of lactose to a maximum of 50 g, hydrogen in breath was measured at 15 min intervals for 3 h. A rise of 20 ppm above baseline was considered suggestive of lactose malabsorption.

RESULTS:

Of 108 children screened, organic causes were found in 46 children. Sixty-two patients without any organic cause underwent hydrogen breath test. Lactose hydrogen breath test (HBT) was positive in 36 of 62 (58%), while 11 (17%) had positive HBT with glucose suggestive of small intestinal bacterial overgrowth (SIBO). Twenty out of 34 (59%) improved on lactose free diet while 8 out of 11 (72%) children of SIBO improved on antibiotics.

CONCLUSIONS:

Lactose malabsorption was seen in 58% of children with non-organic chronic abdominal pain.

KEYWORDS:

Hydrogen breath tests; Recurrent acute pancreatitis; Small intestinal bacterial overgrowth

PMID:
28589304
DOI:
10.1007/s12664-017-0750-8
[Indexed for MEDLINE]

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