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J Psychiatr Res. 2017 Oct;93:37-49. doi: 10.1016/j.jpsychires.2017.05.009. Epub 2017 May 26.

Schizophrenia: A review of potential biomarkers.

Author information

1
Psychiatric Diseases Research Group, Galicia Sur Health Research Institute. Complexo Hospitalario Universitario de Vigo (CHUVI), SERGAS, CIBERSAM, Spain.
2
Neurology Research Group, Galicia Sur Health Research Institute. Complexo Hospitalario Universitario de Vigo (CHUVI), SERGAS, CIBERSAM, Spain.
3
Psychiatric Diseases Research Group, Galicia Sur Health Research Institute. Complexo Hospitalario Universitario de Vigo (CHUVI), SERGAS, CIBERSAM, Spain. Electronic address: roberto.carlos.agis.balboa@sergas.es.

Abstract

OBJECTIVES:

Understanding the biological process and progression of schizophrenia is the first step to developing novel approaches and new interventions. Research on new biomarkers is extremely important when the goal is an early diagnosis (prediction) and precise theranostics. The objective of this review is to understand the research on biomarkers and their effects in schizophrenia to synthesize the role of these new advances.

METHODS:

In this review, we search and review publications in databases in accordance with established limits and specific objectives. We look at particular endpoints such as the category of biomarkers, laboratory techniques and the results/conclusions of the selected publications.

RESULTS:

The investigation of biomarkers and their potential as a predictor, diagnosis instrument and therapeutic orientation, requires an appropriate methodological strategy. In this review, we found different laboratory techniques to identify biomarkers and their function in schizophrenia.

CONCLUSION:

The consolidation of this information will provide a large-scale application network of schizophrenia biomarkers.

[Indexed for MEDLINE]

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