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Dermatol Clin. 2017 Jul;35(3):291-297. doi: 10.1016/j.det.2017.02.003. Epub 2017 Apr 22.

The Long-Term Course of Atopic Dermatitis.

Author information

1
Department of Dermatology, University of California San Francisco (UCSF), 2340 Sutter Street, N421, San Francisco, CA 94115, USA. Electronic address: katrina.abuabara@ucsf.edu.
2
Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, Keppel St, Bloomsbury, London WC1E 7HT, UK.
3
Department of Dermatology, University of Pennsylvania Perelman School of Medicine, 3400 Civic Center Boulevard, Philadelphia, PA 19104, USA; Department of Biostatistics and Epidemiology, University of Pennsylvania Perelman School of Medicine, 3400 Civic Center Boulevard, Philadelphia, PA 19104, USA.

Abstract

Atopic dermatitis (AD) is a chronic, relapsing condition, meaning that the intensity of symptoms usually fluctuates over time. Changes in skin physiology may be evident from birth, suggesting that AD may be a lifelong condition marked by intermittent symptoms/disease activity. Methodological considerations for studying the long-term course of AD are reviewed in detail. Improved measurement of the frequency and duration of active disease periods can help to elucidate more about the clinical course AD and the role of treatment in long-term outcomes.

KEYWORDS:

Atopic dermatitis; Atopic eczema; Clinical course; Eczema; Epidemiology; Natural history

PMID:
28577798
PMCID:
PMC5612374
DOI:
10.1016/j.det.2017.02.003
[Indexed for MEDLINE]
Free PMC Article

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