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Obes Surg. 2017 Nov;27(11):2818-2828. doi: 10.1007/s11695-017-2709-3.

Five-Year Outcomes: Laparoscopic Greater Curvature Plication for Treatment of Morbid Obesity.

Author information

First Faculty of Medicine, Charles University, Prague, Czech Republic.
OB Klinika a.s, Pod Krejcarkem 975, 130 00, Prague 3, Czech Republic.
Division of Scientific Research Writing, Medwrite Medical Communications, Maiden Rock, WI, USA.
General University Hospital, Prague, and Faculty of Health Sciences, Palacky University, Olomouc, Czech Republic.
OB Klinika a.s, Pod Krejcarkem 975, 130 00, Prague 3, Czech Republic.
Statistical Analysis and Quality of Life Assessment, McGlennon MotiMetrics, Maiden Rock, WI, USA.
First Faculty of Medicine, Charles University, Prague, Czech Republic.



Laparoscopic greater curvature plication (LGCP) is a newer metabolic/bariatric surgical procedure that requires no resection, bypass, or implantable device. We report outcomes in a cohort of LGCP patients at 5-year follow-up.


Body mass index (BMI, kg/m2) evolution, excess weight loss (%EWL), excess BMI loss (%EBMIL), and total weight loss (%TWL) were recorded. Repeated measures analysis of variance (ANOVA) was used to assess BMI change over 5 years. Two-step cluster analysis was used to profile LGCP patients according to significant characteristics relative to successful 5-year weight loss.


Of patients entering the study between 2010 and 2011 with complete weight data through 5-year follow-up (86.9%, 212/244), mean age was 45.8 ± 10.9 years; mean baseline BMI, 41.4 ± 5.5 (81.6% women); 58 patients (27.4%) had type 2 diabetes. Mean operative time was 69.0 min; mean hospitalization, 38 h (24-72). ANOVA indicated a significant BMI reduction out to 2 years (p < 0.001), a plateau at 3 and 4 years, and a moderate but significant BMI increase at 5 years (p < 0.01). EBMIL at 1, 2, 3, 4, and 5 years was as follows: 50.7 ± 9.1%, 61.5 ± 8.1%, 60.2 ± 7.0%, 58.5 ± 7.0%, and 56.8 ± 6.3%. At 5 years, 79.2% (168/212) of patients were successful; 20.8% (44/212) experienced a suboptimal weight outcome; mean weight regain, 9.2%. Cluster analysis identified four distinct LGCP patient profiles. Diabetes improvement rate was 65.5%. There were 12 reoperations (4.9%): 4 emergency (1.6%) and 8 (3.3%) elective. There was no mortality.


At 5-year follow-up, LGCP proved to be safe and effective, with 56.8% EBMIL and a low rate of complications.


Diabetes; LGCP; Laparoscopic greater curvature plication; Obesity

[Indexed for MEDLINE]

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