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Int Rev Neurobiol. 2017;132:79-127. doi: 10.1016/bs.irn.2017.01.007. Epub 2017 Mar 27.

Advances in the Clinical Differential Diagnosis of Parkinson's Disease.

Author information

1
Institute of Neurology, UCL, London, United Kingdom.
2
University of Athens Medical School, Hospital Attikon, Athens, Greece; HYGEIA Hospital, Athens, Greece; Philipps University, Marburg, Germany. Electronic address: mariastamelou@gmail.com.

Abstract

The differential diagnosis of Parkinson's disease has widened considerably in recent years. This chapter aims to summarize the current knowledge on the clinical differential diagnoses of sporadic Parkinson's disease. As the number of monogenic familial Parkinson's disease variants and risk factors is growing, so is the number of appreciated etiologies of atypical parkinsonian and other pallidopyramidal syndromes. This work aims at summarizing the current knowledge on both motor and nonmotor neurological signs and symptoms that aid the clinical diagnosis of Parkinson's disease and its differential diagnoses.

KEYWORDS:

Atypical parkinsonism; Familial genetic Parkinson's disease; Levodopa response; Phenotypical characterization; Secondary parkinsonism

PMID:
28554422
DOI:
10.1016/bs.irn.2017.01.007
[Indexed for MEDLINE]

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