Format

Send to

Choose Destination
Gastrointest Endosc. 2018 Feb;87(2):469-475. doi: 10.1016/j.gie.2017.05.013. Epub 2017 May 24.

EUS-guided fine-needle core liver biopsy sampling using a novel 19-gauge needle with modified 1-pass, 1 actuation wet suction technique.

Author information

1
Borland Groover Clinic, Jacksonville, Florida, USA; Baptist Medical Center, Jacksonville, Florida, USA.
2
Department of Surgery, University of California at Los Angeles, Los Angeles, California, USA.
3
University of North Carolina, Chapel Hill, North Carolina, USA.
4
Borland Groover Clinic, Jacksonville, Florida, USA.
5
Baptist Medical Center, Jacksonville, Florida, USA.
6
Department of Surgery, University of California at Los Angeles, Los Angeles, California, USA; Department of Medicine, University of California at Los Angeles, Los Angeles, California, USA.

Abstract

BACKGROUND AND AIMS:

EUS-guided fine-needle core biopsy sampling is a safe and effective technique for diagnosis of focal liver lesions. However, data are limited in its role in parenchymal disease. We evaluated the utility of EUS-guided parenchymal liver biopsy sampling with a modified 1-pass wet suction technique (EUS-modified liver biopsy sampling [EUS-MLB]) in patients with unexplained increase in liver-associated tests.

METHODS:

We retrospectively evaluated the safety and efficacy of EUS-MLB in patients referred for EUS to evaluate for biliary obstruction and pancreatic disorders but with associated unexplained liver tests. EUS-MLB was performed during the same session after biliary obstruction was excluded.

RESULTS:

One hundred sixty-five consecutive patients underwent EUS-MLB. The median age was 52 years (interquartile range [IQR], 42-65). Sixty-eight patients (41%) were men. The median of the maximum intact core tissue length was 2.4 cm (IQR, 1.8-3.5). The median total specimen length (TSL) was 6 cm (IQR, 4.3-8). The median number of complete portal tracts (CPTs) per TSL was 18 (IQR, 13- 24). The mean number of CPTs per sample length was 7.5 cm. Adverse events were uncommon (1.8%) and included abdominal pain and self-limited hematoma.

CONCLUSIONS:

EUS-guided fine-needle biopsy sampling using a novel 19-gauge core needle with a modified 1-pass 1 actuation wet suction technique (EUS-MLB) is a safe and effective way to evaluate patients with unexplained liver tests abnormalities who are undergoing EUS for exclusion of biliary obstruction.

PMID:
28551024
DOI:
10.1016/j.gie.2017.05.013
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center