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Curr Med Chem. 2017 May 23. doi: 10.2174/0929867324666170523123010. [Epub ahead of print]

Modulation of Aquaporins by dietary patterns and plant bioactive compounds.

Author information

1
Dipartimento di Bioscienze, Biotecnologie e Biofarmaceutica, UniversitĂ  degli Studi di Bari "Aldo Moro" - via E. Orabona - 70125 Bari . Italy.
2
Department of Biosciences, Biotechnologies and Biopharmaceu.cs, University of Bari. Italy.
3
Department of Biosciences, Biotechnologies and Biopharmaceu.cs, University of Bari, Bari. Italy.
4
Clinica Medica "A. Murri", Department of Biomedical Sciences and Human Oncology, Medical School, University of Bari, Bari. Italy.
5
Clinica Medica "A. Murri", Department of Biomedical Sciences and Human Oncology, Medical School, University of Bari "Aldo Moro", Bari. Italy.

Abstract

Healthful dietary patterns and bioactive compounds supplementation can be adopted as simple and easy intervention to prevent, attenuate or cure clinical disorders, especially when it comes degenerative and chronic diseases. In the recent years, a growing body of evidence indicates Aquaporins (AQPs), a family of membrane channel proteins widely expressed in the human body, among the targets underlying the beneficial action played by some food nutrients and phytochemical compounds. Here, we provide an overview of what is known regarding the AQP modulation exerted by healthful dietary patterns and plant polyphenols.

KEYWORDS:

brain edema.; functional food; metabolic syndrome; nutraceuticals; polyphenols

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