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Environ Sci Pollut Res Int. 2017 Jul;24(19):15949-15958. doi: 10.1007/s11356-017-8928-2. Epub 2017 May 24.

The association between air pollutants and autism spectrum disorders.

Author information

1
Department of Epidemiology and Biostatistics, School of Public Health, Harbin Medical University, 157 Baojian Road, Harbin, 150081, China.
2
School of Public Health and Community Medicine, University of Washington Autism Center, University of Washington, Seattle, USA.
3
Department of Biostatistics, School of Public Health and Community Medicine, University of Washington, Seattle, WA, 98195, USA. 319015685@qq.com.
4
Department of Epidemiology and Biostatistics, School of Public Health, Harbin Medical University, 157 Baojian Road, Harbin, 150081, China. houyan@ems.hrbmu.edu.cn.

Abstract

Autism spectrum disorders are a member of the pervasive developmental disorders (PDDs) that have been increasing dramatically since described by Leo Kanner in 1943. In the past decade, the number of epidemiological publications addressing air pollution exposures and autism has grown correspondingly, but the association is still unclear. Whether air pollutants play a causal role and which substances are related with autism requires further study. We systematically reviewed the literature from 2005 to 2016 in MEDLINE (National Library of Medicine), Web of Science, and PubMed and summarized the association between different air pollutants and autism. Furthermore, we further discussed the exposure time window and potential confounders that should be considered in the association analysis studies. Our objective is to summarize the association between different air pollutants and autism with literature, which has been published since 2005, and explore whether the exposure time window and potential confounders have influence on this association. These results could provide more comprehensive information about the association between air pollutants and autism and be helpful towards further validation study. Graphical abstract ᅟ.

KEYWORDS:

Air pollutant; Association; Autism; Autism spectrum disorders

PMID:
28540549
DOI:
10.1007/s11356-017-8928-2
[Indexed for MEDLINE]

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