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J Bone Jt Infect. 2017 Apr 5;2(3):136-142. doi: 10.7150/jbji.18408. eCollection 2017.

Brucella melitensis prosthetic joint infection.

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Department of Infectious Diseases, Cantonal Hospital of St. Gallen, St. Gallen.
Department of Orthopaedics and Traumatology, Cantonal Hospital of St. Gallen, St. Gallen.
Department of Infectious Diseases, Bern University Hospital, University of Bern, Bern, Switzerland.


Periprosthetic joint infection (PJI) due to Brucella spp. is rare. We report a case in a 75-year-old man and review 29 additional cases identified in a literature search. The diagnosis of Brucella PJI is challenging, in particular in non-endemic countries. Serological tests prior to joint aspiration or surgical intervention are reasonable. Involvement of infection control and timely information to laboratory personnel is mandatory upon diagnosis. There is no uniform treatment concept, neither with respect to surgical intervention nor for the duration of antimicrobials. Most cases have a successful outcome, irrespective of surgical modality, and with an antimicrobial combination regimen for 12 or more weeks.


Brucella; Periprosthetic joint infection

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