Mother Nature in Eczema: Maternal Factors Influencing Atopic Dermatitis

Pediatr Dermatol. 2017 May;34(3):240-246. doi: 10.1111/pde.13149.

Abstract

Atopic dermatitis (AD) is a highly prevalent chronic inflammatory skin disease. Current knowledge about the etiology of AD suggests that it is multifactorial and involves the interaction of several factors, including environmental triggers, genetics, immunologic factors, and skin barrier dysfunction. The prenatal environment has a significant influence on fetal development, including the maturation of skin barrier function. This review summarizes maternal factors that have been reported to influence the development of AD in offspring, including maternal genetics, nutrition, breastfeeding, environment, and behaviors.

Publication types

  • Review

MeSH terms

  • Eczema / epidemiology
  • Eczema / genetics*
  • Eczema / immunology*
  • Female
  • Genetic Predisposition to Disease*
  • Humans
  • Male
  • Maternal Age
  • Maternal Behavior*
  • Maternal Health*
  • Preexisting Condition Coverage
  • Pregnancy
  • Risk Factors
  • Severity of Illness Index