Format

Send to

Choose Destination
Clin Infect Dis. 2017 Jul 1;65(1):150-153. doi: 10.1093/cid/cix245.

Infectivity of Post-Kala-azar Dermal Leishmaniasis Patients to Sand Flies: Revisiting a Proof of Concept in the Context of the Kala-azar Elimination Program in the Indian Subcontinent.

Author information

1
World Health Organization Collaborating Centre for Leishmaniasis, Laboratory of Medical Entomology, National Centre for Microbiology, Instituto de Salud Carlos III, Madrid, Spain.
2
International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka.
3
World Health Organization Collaborating Center for Leishmaniasis, Laboratory of Leishmaniasis and Chagas, National Centre for Microbiology, Instituto de Salud Carlos III, Madrid, Spain.
4
Drugs for Neglected Diseases Initiative, Geneva, Switzerland.
5
Department of Epidemiology and Biostatistics, School of Medicine, University of California, San Francisco.

Abstract

We compared xenodiagnosis with quantitative polymerase chain reaction in skin biopsies from 3 patients with maculopapular or nodular post-kala-azar dermal leishmaniasis (PKDL). All patients infected sand flies. Parasite loads in skin varied from 1428 to 63 058 parasites per microgram. PKDL detection and treatment are important missing components of the kala-azar elimination program.

KEYWORDS:

control; leishmaniasis; post–kala-azar dermal leishmaniasis; xenodiagnosis

PMID:
28520851
PMCID:
PMC5848257
DOI:
10.1093/cid/cix245
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for Silverchair Information Systems Icon for PubMed Central
Loading ...
Support Center