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Semergen. 2018 Mar;44(2):121-124. doi: 10.1016/j.semerg.2017.01.012. Epub 2017 May 13.

[What medication should be prescribed to a patient with coeliac disease?]

[Article in Spanish]

Author information

1
Servicio de Farmacia de Atención Primaria, Dirección de Atención Primaria Sector Teruel, Centro de Salud Teruel Ensanche, Teruel, España. Electronic address: cperezd@salud.aragon.es.
2
Dirección de Atención Primaria Sector Teruel, Centro de Salud Teruel Ensanche, Teruel, España.
3
Servicio de Farmacia, Hospital Universitario Miguel Servet, Zaragoza, España.

Abstract

Coeliac disease is a permanent intolerance to gluten proteins from wheat, rye, barley and triticale. Although strict adherence is complicated, the only effective treatment is a gluten-free diet throughout life. Some drugs contain starch as an excipient, and there is a risk related to the gluten content, which must be avoided in these patients. Current legislation requires the analysis of the protein content of wheat starch, or the absence of starches from another source where rice, maize, or potato starches are used as excipients. But, it does not specify that reference should be made to traces of gluten that are residues of the process of production of the active ingredient. As regards the case described, there needs to be awareness of the importance of adequately informing patients and reviewing/updating current legislation to ensure the safe use of drugs.

KEYWORDS:

Almidón; Coeliac disease; Enfermedad celiaca; Excipientes de declaración obligatoria; Gluten; Mandatory statement of excipients; Starch

PMID:
28511881
DOI:
10.1016/j.semerg.2017.01.012
[Indexed for MEDLINE]

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