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Pediatr Clin North Am. 2017 Jun;64(3):685-706. doi: 10.1016/j.pcl.2017.01.010.

Pancreatic Disorders.

Author information

1
Division of Pediatric Gastroenterology, Stead Family Department of Pediatrics, University of Iowa Carver College of Medicine, BT 1120-C, 200 Hawkins Drive, Iowa City, IA 52242, USA. Electronic address: aliye-uc@uiowa.edu.
2
Section of Pediatric Gastroenterology, Hepatology, and Nutrition, Texas Children's Hospital, Baylor College of Medicine, 6701 Fannin Street, Clinical Care Tower, 1010, Houston, TX 77030, USA.

Abstract

Once considered uncommon, pancreatic diseases are increasingly recognized in the pediatric age group. Acute pancreatitis, acute recurrent pancreatitis, and chronic pancreatitis occur in children with an incidence approaching that of adults. Risk factors are broad, prompting the need for a completely different diagnostic and therapeutic approach in children. Although cystic fibrosis remains the most common cause of exocrine pancreatic insufficiency, other causes such as chronic pancreatitis may be as common as Shwachman Diamond syndrome. Long-term effects of pancreatic diseases may be staggering, as children suffer from significant disease burden, high economic cost, nutritional deficiencies, pancreatogenic diabetes, and potentially pancreatic cancer.

KEYWORDS:

Acute pancreatitis; Acute recurrent pancreatitis; Chronic pancreatitis; Diabetes; Pancreatic insufficiency

PMID:
28502446
PMCID:
PMC5604472
DOI:
10.1016/j.pcl.2017.01.010
[Indexed for MEDLINE]
Free PMC Article

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