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Pregnancy Hypertens. 2017 Apr;8:6-8. doi: 10.1016/j.preghy.2017.02.003. Epub 2017 Mar 1.

Alteration of serum adropin level in preeclampsia.

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Women's Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Women's Hospital, School of Medicine, Zhejiang University, Hangzhou, China; Key Laboratory of Women's Reproductive Health of Zhejiang Province, China; Key Laboratory of Reproductive Genetics of the Ministry of Education, China. Electronic address:


To clarify the alterations in serum adropin and preptin concentrations in preeclampsia, we determined serum adropin and preptin levels in 29 women with normal pregnancy and 32 women with preeclampsia. We found that maternal age, body mass index and fetal gender were not significantly different between two groups; however, blood pressure, gestational age and neonatal birth weight were significantly different. Serum adropin levels were significantly increased in women with preeclampsia compared with those with normal pregnancy but there were no significant differences in preptin levels. An increase in maternal serum adropin level was found in preeclampsia, and this may be a compensation for pregnancy complicated with preeclampsia.


Adropin; Preeclampsia; Pregnancy; Preptin

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