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Adv Chronic Kidney Dis. 2017 May;24(3):150-153. doi: 10.1053/j.ackd.2017.03.005.

Recent Advances in Magnetic Resonance Imaging Assessment of Renal Fibrosis.

Author information

1
Selzman Institute for Kidney Health and Section of Nephrology, Department of Medicine, Baylor College of Medicine, Houston, TX; and Center for Translational Research on Inflammatory Diseases (CTRID) and Renal Section, Michael E. DeBakey Veterans Affairs Medical Center, Houston, TX.
2
Selzman Institute for Kidney Health and Section of Nephrology, Department of Medicine, Baylor College of Medicine, Houston, TX; and Center for Translational Research on Inflammatory Diseases (CTRID) and Renal Section, Michael E. DeBakey Veterans Affairs Medical Center, Houston, TX. Electronic address: yanlinw@bcm.edu.

Abstract

CKD is a global public health problem. Renal fibrosis is a final common pathway leading to progressive loss of function in CKD. The degree of renal fibrosis predicts the prognosis of CKD. Recent studies have shown that bone marrow-derived fibroblasts contribute significantly to the development of renal fibrosis, which may yield novel therapeutic strategy for fibrotic kidney disease. Therefore, it is imperative to accurately assess the degree of renal fibrosis noninvasively to identify those patients who can benefit from antifibrotic therapy. In this review, we summarize recent advances in the assessment of renal fibrosis by magnetic resonance imaging.

KEYWORDS:

Chronic kidney disease; Extracellular matrix; Fibroblast; Fibrosis; Magnetic resonance imaging

PMID:
28501077
PMCID:
PMC5433256
DOI:
10.1053/j.ackd.2017.03.005
[Indexed for MEDLINE]
Free PMC Article

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